Transiently Reduced PI3K/Akt Activity Drives the Development of Regulatory Function in Antigen-Stimulated Naïve T-Cells

Regulatory T-cells (T(regs)) are central for immune homeostasis and divided in thymus-derived natural T(regs) and peripherally induced iT(reg). However, while phenotype and function of iT(regs) are well known, a remarkable lack exists in knowledge about signaling mechanisms leading to their generati...

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Detalles Bibliográficos
Autores principales: Etemire, Eloho, Krull, Marco, Hasenberg, Mike, Reichardt, Peter, Gunzer, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708928/
https://www.ncbi.nlm.nih.gov/pubmed/23874604
http://dx.doi.org/10.1371/journal.pone.0068378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708928/
https://www.ncbi.nlm.nih.gov/pubmed/23874604
http://dx.doi.org/10.1371/journal.pone.0068378

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