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Transiently Reduced PI3K/Akt Activity Drives the Development of Regulatory Function in Antigen-Stimulated Naïve T-Cells
Regulatory T-cells (T(regs)) are central for immune homeostasis and divided in thymus-derived natural T(regs) and peripherally induced iT(reg). However, while phenotype and function of iT(regs) are well known, a remarkable lack exists in knowledge about signaling mechanisms leading to their generati...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708928/ https://www.ncbi.nlm.nih.gov/pubmed/23874604 http://dx.doi.org/10.1371/journal.pone.0068378 |