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BiP Negatively Affects Ricin Transport

The AB plant toxin ricin binds both glycoproteins and glycolipids at the cell surface via its B subunit. After binding, ricin is endocytosed and then transported retrogradely through the Golgi to the endoplasmic reticulum (ER). In the ER, the A subunit is retrotranslocated to the cytosol in a chaper...

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Detalles Bibliográficos
Autores principales: Gregers, Tone F., Skånland, Sigrid S., Wälchli, Sébastien, Bakke, Oddmund, Sandvig, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709273/
https://www.ncbi.nlm.nih.gov/pubmed/23666197
http://dx.doi.org/10.3390/toxins5050969