Cargando…
BiP Negatively Affects Ricin Transport
The AB plant toxin ricin binds both glycoproteins and glycolipids at the cell surface via its B subunit. After binding, ricin is endocytosed and then transported retrogradely through the Golgi to the endoplasmic reticulum (ER). In the ER, the A subunit is retrotranslocated to the cytosol in a chaper...
Autores principales: | Gregers, Tone F., Skånland, Sigrid S., Wälchli, Sébastien, Bakke, Oddmund, Sandvig, Kirsten |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709273/ https://www.ncbi.nlm.nih.gov/pubmed/23666197 http://dx.doi.org/10.3390/toxins5050969 |
Ejemplares similares
-
SNX4 in Complex with Clathrin and Dynein: Implications for Endosome Movement
por: Skånland, Sigrid S., et al.
Publicado: (2009) -
Intracellular Transport and Cytotoxicity of the Protein Toxin Ricin
por: Sowa-Rogozińska, Natalia, et al.
Publicado: (2019) -
Role of Phospholipase A(2) in Retrograde Transport of Ricin
por: Klokk, Tove Irene, et al.
Publicado: (2011) -
Antibody-Mediated Inhibition of Ricin Toxin Retrograde Transport
por: Yermakova, Anastasiya, et al.
Publicado: (2014) -
The Protein Toxins Ricin and Shiga Toxin as Tools to Explore Cellular Mechanisms of Internalization and Intracellular Transport
por: Sandvig, Kirsten, et al.
Publicado: (2021)