Digitoxin induces apoptosis in cancer cells by inhibiting nuclear factor of activated T-cells-driven c-MYC expression

BACKGROUND: Cardiac glycosides such as digitoxin have been shown to directly cause apoptotic death of cancer cells both in vitro, and in vivo. However, the mechanism connecting cardiac glycoside action to apoptosis is not known. It has been reported that compounds resembling digitoxin are able to re...

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Detalles Bibliográficos
Autores principales: Yang, Qing Feng, Dalgard, Clifton L., Eidelman, Ofer, Jozwik, Catherine, Pollard, Bette S., Srivastava, Meera, Pollard, Harvey B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709410/
https://www.ncbi.nlm.nih.gov/pubmed/23858296
http://dx.doi.org/10.4103/1477-3163.112268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709410/
https://www.ncbi.nlm.nih.gov/pubmed/23858296
http://dx.doi.org/10.4103/1477-3163.112268

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