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Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31

Epithelial ovarian cancer (EOC) has a heritable component that remains to be fully characterized. Most identified common susceptibility variants lie in non-protein-coding sequences. We hypothesized that variants in the 3′ untranslated region at putative microRNA (miRNA) binding sites represent funct...

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Autores principales: Permuth-Wey, Jennifer, Lawrenson, Kate, Shen, Howard C., Velkova, Aneliya, Tyrer, Jonathan P., Chen, Zhihua, Lin, Hui-Yi, Chen, Y. Ann, Tsai, Ya-Yu, Qu, Xiaotao, Ramus, Susan J., Karevan, Rod, Lee, Janet, Lee, Nathan, Larson, Melissa C., Aben, Katja K., Anton-Culver, Hoda, Antonenkova, Natalia, Antoniou, Antonis, Armasu, Sebastian M., Bacot, François, Baglietto, Laura, Bandera, Elisa V., Barnholtz-Sloan, Jill, Beckmann, Matthias W., Birrer, Michael J., Bloom, Greg, Bogdanova, Natalia, Brinton, Louise A., Brooks-Wilson, Angela, Brown, Robert, Butzow, Ralf, Cai, Qiuyin, Campbell, Ian, Chang-Claude, Jenny, Chanock, Stephen, Chenevix-Trench, Georgia, Cheng, Jin Q., Cicek, Mine S., Coetzee, Gerhard A., Cook, Linda S., Couch, Fergus J., Cramer, Daniel W., Cunningham, Julie M., Dansonka-Mieszkowska, Agnieszka, Despierre, Evelyn, Doherty, Jennifer A, Dörk, Thilo, du Bois, Andreas, Dürst, Matthias, Easton, Douglas F, Eccles, Diana, Edwards, Robert, Ekici, Arif B., Fasching, Peter A., Fenstermacher, David A., Flanagan, James M., Garcia-Closas, Montserrat, Gentry-Maharaj, Aleksandra, Giles, Graham G., Glasspool, Rosalind M., Gonzalez-Bosquet, Jesus, Goodman, Marc T., Gore, Martin, Górski, Bohdan, Gronwald, Jacek, Hall, Per, Halle, Mari K., Harter, Philipp, Heitz, Florian, Hillemanns, Peter, Hoatlin, Maureen, Høgdall, Claus K., Høgdall, Estrid, Hosono, Satoyo, Jakubowska, Anna, Jensen, Allan, Jim, Heather, Kalli, Kimberly R., Karlan, Beth Y., Kaye, Stanley B., Kelemen, Linda E., Kiemeney, Lambertus A., Kikkawa, Fumitaka, Konecny, Gottfried E., Krakstad, Camilla, Kjaer, Susanne Krüger, Kupryjanczyk, Jolanta, Lambrechts, Diether, Lambrechts, Sandrina, Lancaster, Johnathan M., Le, Nhu D., Leminen, Arto, Levine, Douglas A., Liang, Dong, Lim, Boon Kiong, Lin, Jie, Lissowska, Jolanta, Lu, Karen H., Lubiński, Jan, Lurie, Galina, Massuger, Leon F.A.G., Matsuo, Keitaro, McGuire, Valerie, McLaughlin, John R, Menon, Usha, Modugno, Francesmary, Moysich, Kirsten B., Nakanishi, Toru, Narod, Steven A., Nedergaard, Lotte, Ness, Roberta B., Nevanlinna, Heli, Nickels, Stefan, Noushmehr, Houtan, Odunsi, Kunle, Olson, Sara H., Orlow, Irene, Paul, James, Pearce, Celeste L, Pejovic, Tanja, Pelttari, Liisa M., Pike, Malcolm C., Poole, Elizabeth M., Raska, Paola, Renner, Stefan P., Risch, Harvey A., Rodriguez-Rodriguez, Lorna, Rossing, Mary Anne, Rudolph, Anja, Runnebaum, Ingo B., Rzepecka, Iwona K., Salvesen, Helga B., Schwaab, Ira, Severi, Gianluca, Shridhar, Vijayalakshmi, Shu, Xiao-Ou, Shvetsov, Yurii B., Sieh, Weiva, Song, Honglin, Southey, Melissa C., Spiewankiewicz, Beata, Stram, Daniel, Sutphen, Rebecca, Teo, Soo-Hwang, Terry, Kathryn L., Tessier, Daniel C., Thompson, Pamela J., Tworoger, Shelley S., van Altena, Anne M., Vergote, Ignace, Vierkant, Robert A., Vincent, Daniel, Vitonis, Allison F., Wang-Gohrke, Shan, Weber, Rachel Palmieri, Wentzensen, Nicolas, Whittemore, Alice S., Wik, Elisabeth, Wilkens, Lynne R., Winterhoff, Boris, Woo, Yin Ling, Wu, Anna H., Xiang, Yong-Bing, Yang, Hannah P., Zheng, Wei, Ziogas, Argyrios, Zulkifli, Famida, Phelan, Catherine M., Iversen, Edwin, Schildkraut, Joellen M., Berchuck, Andrew, Fridley, Brooke L., Goode, Ellen L., Pharoah, Paul D. P., Monteiro, Alvaro N.A., Sellers, Thomas A., Gayther, Simon A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709460/
https://www.ncbi.nlm.nih.gov/pubmed/23535648
http://dx.doi.org/10.1038/ncomms2613