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Fork sensing and strand switching control antagonistic activities of RecQ helicases

RecQ helicases have essential roles in maintaining genome stability during replication and in controlling double-strand break repair by homologous recombination. Little is known about how the different RecQ helicases found in higher eukaryotes achieve their specialized and partially opposing functio...

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Detalles Bibliográficos
Autores principales: Klaue, Daniel, Kobbe, Daniela, Kemmerich, Felix, Kozikowska, Alicja, Puchta, Holger, Seidel, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709500/
https://www.ncbi.nlm.nih.gov/pubmed/23771268
http://dx.doi.org/10.1038/ncomms3024