Upregulation of TRIM5α gene expression after live-attenuated simian immunodeficiency virus vaccination in Mauritian cynomolgus macaques, but TRIM5α genotype has no impact on virus acquisition or vaccination outcome

Polymorphism in the TRIM5α/TRIMcyp gene, which interacts with the lentiviral capsid, has been shown to impact on simian immunodeficiency virus (SIV) replication in certain macaque species. Here, in the context of a live-attenuated SIV vaccine study conducted in Mauritian-origin cynomolgus macaques (...

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Detalles Bibliográficos
Autores principales: Mattiuzzo, Giada, Rose, Nicola J., Almond, Neil, Towers, Greg J., Berry, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2013
Materias:
Animal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709606/
https://www.ncbi.nlm.nih.gov/pubmed/23152371
http://dx.doi.org/10.1099/vir.0.047795-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709606/
https://www.ncbi.nlm.nih.gov/pubmed/23152371
http://dx.doi.org/10.1099/vir.0.047795-0

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