Cargando…

Creation of a completely helper cell-dependent recombinant morbillivirus

We have created a completely helper cell-dependent morbillivirus by modifying the genome to remove the coding sequence of the phosphoprotein (P) and recovering the recombinant virus in a cell line constitutively expressing the P protein. The P protein-deleted virus (P(−)) grew very inefficiently unl...

Descripción completa

Detalles Bibliográficos
Autores principales: Baron, Jana, Baron, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709626/
https://www.ncbi.nlm.nih.gov/pubmed/23426357
http://dx.doi.org/10.1099/vir.0.050872-0