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Creation of a completely helper cell-dependent recombinant morbillivirus
We have created a completely helper cell-dependent morbillivirus by modifying the genome to remove the coding sequence of the phosphoprotein (P) and recovering the recombinant virus in a cell line constitutively expressing the P protein. The P protein-deleted virus (P(−)) grew very inefficiently unl...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for General Microbiology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709626/ https://www.ncbi.nlm.nih.gov/pubmed/23426357 http://dx.doi.org/10.1099/vir.0.050872-0 |