Ectopic expression of miR-34a enhances radiosensitivity of non-small cell lung cancer cells, partly by suppressing the LyGDI signaling pathway

miR-34a is transcriptionally induced by the tumor suppressor gene p53, which is often downregulated in non-small cell lung cancer (NSCLC). To address whether the downstream signal of miR-34a is sufficient to induce apoptosis and to alter cellular radiosensitivity, a chemical synthetic miR-34a mimic...

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Detalles Bibliográficos
Autores principales: Duan, Weiming, Xu, Yaxiang, Dong, YuJin, Cao, Lili, Tong, Jian, Zhou, Xinwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709664/
https://www.ncbi.nlm.nih.gov/pubmed/23349340
http://dx.doi.org/10.1093/jrr/rrs136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709664/
https://www.ncbi.nlm.nih.gov/pubmed/23349340
http://dx.doi.org/10.1093/jrr/rrs136

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