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Cisplatin Protects against Acute Liver Failure by Inhibiting Nuclear HMGB1 Release

Cisplatin is one of the most widely used chemical drugs for anticancer treatment. Recent studies have focused on the ability of cisplatin to retain the high mobility group box 1 (HMGB1) protein in cisplatin-DNA adducts, thereby preventing its release from the nucleus. Because HMGB1 is a powerful inf...

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Detalles Bibliográficos
Autores principales: Li, Xun, Wang, Li-Kun, Wang, Lu-Wen, Han, Xiao-Qun, Yang, Fan, Gong, Zuo-Jiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709729/
https://www.ncbi.nlm.nih.gov/pubmed/23712360
http://dx.doi.org/10.3390/ijms140611224