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Enhanced Inhibition of Prostate Tumor Growth by Dual Targeting the Androgen Receptor and the Regulatory Subunit Type Iα of Protein Kinase A in Vivo

Progression to castration resistance is a major problem in the treatment of advanced prostate cancer and is likely to be driven by activation of several molecular pathways, including androgen receptor (AR) and cyclic AMP-dependent protein kinase A (PKA). In this study, we examined the therapeutic ef...

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Detalles Bibliográficos
Autores principales: Eder, Iris E., Egger, Martina, Neuwirt, Hannes, Seifarth, Christof, Maddalo, Danilo, Desiniotis, Andreas, Schäfer, Georg, Puhr, Martin, Bektic, Jasmin, Cato, Andrew C. B., Klocker, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709765/
https://www.ncbi.nlm.nih.gov/pubmed/23736698
http://dx.doi.org/10.3390/ijms140611942