Design, Synthesis, Biological Activity and Molecular Dynamics Studies of Specific Protein Tyrosine Phosphatase 1B Inhibitors over SHP-2

Over expressing in PTPN1 (encoding Protein tyrosine phosphatase 1B, PTP1B), a protein tyrosine phosphatase (PTP) that plays an overall positive role in insulin signaling, is linked to the pathogenesis of diabetes and obesity. The relationship between PTP1B and human diseases exhibits PTP1B as the ta...

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Detalles Bibliográficos
Autores principales: Sun, Su-Xia, Li, Xiao-Bo, Liu, Wen-Bo, Ma, Ying, Wang, Run-Ling, Cheng, Xian-Chao, Wang, Shu-Qing, Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709806/
https://www.ncbi.nlm.nih.gov/pubmed/23774838
http://dx.doi.org/10.3390/ijms140612661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709806/
https://www.ncbi.nlm.nih.gov/pubmed/23774838
http://dx.doi.org/10.3390/ijms140612661

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