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An Apoptosis-Associated Mammary Protein Deficiency Leads to Enhanced Production of IgM Antibodies against Multiple Damage-Associated Molecules
Milk fat globule epidermal growth factor 8 (MFG-E8) is a protein that binds to apoptotic cells by recognizing phosphatidylserine and enhances the engulfment of apoptotic cells by macrophages. Many apoptotic cells are left unengulfed in the germinal centers of the spleen in the MFG-E8-deficient (MFG-...
Autores principales: | Chikazawa, Miho, Otaki, Natsuki, Shibata, Takahiro, Yasueda, Takehiko, Matsuda, Tsukasa, Uchida, Koji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709889/ https://www.ncbi.nlm.nih.gov/pubmed/23874637 http://dx.doi.org/10.1371/journal.pone.0068468 |
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