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Changes in Natural Foxp3(+)Treg but Not Mucosally-Imprinted CD62L(neg)CD38(+)Foxp3(+)Treg in the Circulation of Celiac Disease Patients

BACKGROUND: Celiac disease (CD) is an intestinal inflammation driven by gluten-reactive CD4(+) T cells. Due to lack of selective markers it has not been determined whether defects in inducible regulatory T cell (Treg) differentiation are associated with CD. This is of importance as changes in number...

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Detalles Bibliográficos
Autores principales: van Leeuwen, Marieke A., du Pré, M. Fleur, van Wanrooij, Roy L., de Ruiter, Lilian F., Raatgeep, H. (Rolien) C., Lindenbergh-Kortleve, Dicky J., Mulder, Chris J., de Ridder, Lissy, Escher, Johanna C., Samsom, Janneke N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709933/
https://www.ncbi.nlm.nih.gov/pubmed/23874626
http://dx.doi.org/10.1371/journal.pone.0068432