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Comprehensive analysis of the HEPN superfamily: identification of novel roles in intra-genomic conflicts, defense, pathogenesis and RNA processing

BACKGROUND: The major role of enzymatic toxins that target nucleic acids in biological conflicts at all levels has become increasingly apparent thanks in large part to the advances of comparative genomics. Typically, toxins evolve rapidly hampering the identification of these proteins by sequence an...

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Detalles Bibliográficos
Autores principales: Anantharaman, Vivek, Makarova, Kira S, Burroughs, A Maxwell, Koonin, Eugene V, Aravind, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710099/
https://www.ncbi.nlm.nih.gov/pubmed/23768067
http://dx.doi.org/10.1186/1745-6150-8-15