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MiR-204 down regulates SIRT1 and reverts SIRT1-induced epithelial-mesenchymal transition, anoikis resistance and invasion in gastric cancer cells

BACKGROUND: Our previous studies showed that SIRT1 was over-expressed in gastric cancer specimens and related with lymph node metastasis. However, the mechanism of SIRT1 up-regulation and its association with metastasis in gastric cancer remain unclear. The present study was undertaken to understand...

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Detalles Bibliográficos
Autores principales: Zhang, Lihua, Wang, Xueqing, Chen, Pingsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710153/
https://www.ncbi.nlm.nih.gov/pubmed/23768087
http://dx.doi.org/10.1186/1471-2407-13-290