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Global Rsh-dependent transcription profile of Brucella suis during stringent response unravels adaptation to nutrient starvation and cross-talk with other stress responses

BACKGROUND: In the intracellular pathogen Brucella spp., the activation of the stringent response, a global regulatory network providing rapid adaptation to growth-affecting stress conditions such as nutrient deficiency, is essential for replication in the host. A single, bi-functional enzyme Rsh ca...

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Detalles Bibliográficos
Autores principales: Hanna, Nabil, Ouahrani-Bettache, Safia, Drake, Kenneth L, Adams, L Garry, Köhler, Stephan, Occhialini, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710219/
https://www.ncbi.nlm.nih.gov/pubmed/23834488
http://dx.doi.org/10.1186/1471-2164-14-459