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Cognitive and cerebrovascular improvements following kinin B(1) receptor blockade in Alzheimer’s disease mice

BACKGROUND: Recent evidence suggests that the inducible kinin B(1) receptor (B(1)R) contributes to pathogenic neuroinflammation induced by amyloid-beta (Aβ) peptide. The present study aims at identifying the cellular distribution and potentially detrimental role of B(1)R on cognitive and cerebrovasc...

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Detalles Bibliográficos
Autores principales: Lacoste, Baptiste, Tong, Xin-Kang, Lahjouji, Karim, Couture, Réjean, Hamel, Edith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710240/
https://www.ncbi.nlm.nih.gov/pubmed/23642031
http://dx.doi.org/10.1186/1742-2094-10-57