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Caspase-9, caspase-3 and caspase-7 have distinct roles during intrinsic apoptosis

BACKGROUND: Apoptosis is a form of programmed cell death that is regulated by the Bcl-2 family and caspase family of proteins. The caspase cascade responsible for executing cell death following cytochrome c release is well described; however the distinct roles of caspases-9, -3 and -7 during this pr...

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Detalles Bibliográficos
Autores principales: Brentnall, Matthew, Rodriguez-Menocal, Luis, De Guevara, Rebeka Ladron, Cepero, Enrique, Boise, Lawrence H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710246/
https://www.ncbi.nlm.nih.gov/pubmed/23834359
http://dx.doi.org/10.1186/1471-2121-14-32