Epigenetic screen identifies genotype- specific promoter DNA methylation and oncogenic potential of CHRNB4

Genome-wide association studies have highlighted three major lung cancer susceptibility regions at 15q25.1, 5p15.33 and 6p21.33. To gain insight into the possible mechanistic relevance of the genes in these regions, we investigated the regulation of candidate susceptibility gene expression by epigen...

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Detalles Bibliográficos
Autores principales: Scherf, David B, Sarkisyan, Narek, Jacobsson, Hanna, Claus, Rainer, Bermejo, Justo L, Peil, Barbara, Gu, Lei, Muley, Thomas, Meister, Michael, Dienemann, Hendrik, Plass, Christoph, Risch, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710305/
https://www.ncbi.nlm.nih.gov/pubmed/22945651
http://dx.doi.org/10.1038/onc.2012.344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710305/
https://www.ncbi.nlm.nih.gov/pubmed/22945651
http://dx.doi.org/10.1038/onc.2012.344

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