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Mutual cytokine crosstalk between colon cancer cells and microenvironment initiates development of distant metastases
Tumor growth and cancer development are considered clear examples of Darwinian selection, whereby random mutational events in heterogeneous cancer cell populations that best fit the selective microenvironment are preferred.(1) As a result, cancer cells evolve resistance to apoptosis, hide from immun...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710323/ https://www.ncbi.nlm.nih.gov/pubmed/24058810 http://dx.doi.org/10.4161/jkst.23810 |