Targeting the tumor microenvironment: JAK-STAT3 signaling

Persistent JAK-STAT3 signaling is implicated in many aspects of tumorigenesis. Apart from its tumor-intrinsic effects, STAT3 also exerts tumor-extrinsic effects, supporting tumor survival and metastasis. These involve the regulation of paracrine cytokine signaling, alterations in metastatic sites re...

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Detalles Bibliográficos
Autores principales: Bournazou, Eirini, Bromberg, Jacqueline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710325/
https://www.ncbi.nlm.nih.gov/pubmed/24058812
http://dx.doi.org/10.4161/jkst.23828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710325/
https://www.ncbi.nlm.nih.gov/pubmed/24058812
http://dx.doi.org/10.4161/jkst.23828

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