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Anti-STAT6 CTL activity in Stat6(−/−) mice: A cautionary tale
The generation of germline gene mutations in mice has been an invaluable tool for experimental biology. However, studying immune responses that develop in the absence of a specific protein that could alter thymic selection complicates experimental interpretations. We observed that CD8(+) T cells fro...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710328/ https://www.ncbi.nlm.nih.gov/pubmed/24058815 http://dx.doi.org/10.4161/jkst.24554 |