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Anti-STAT6 CTL activity in Stat6(−/−) mice: A cautionary tale

The generation of germline gene mutations in mice has been an invaluable tool for experimental biology. However, studying immune responses that develop in the absence of a specific protein that could alter thymic selection complicates experimental interpretations. We observed that CD8(+) T cells fro...

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Detalles Bibliográficos
Autores principales: Kaplan, Mark H., Cundiff, Judy K., Smith, Jill Stader, Aldrich, Carla J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710328/
https://www.ncbi.nlm.nih.gov/pubmed/24058815
http://dx.doi.org/10.4161/jkst.24554