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A two-stage mechanism of viral RNA compaction revealed by single molecule fluorescence

Long RNAs often exist as multiple conformers in equilibrium. For the genomes of single-stranded RNA viruses, one of these conformers must include a compacted state allowing the RNA to be confined within the virion. We have used single molecule fluorescence correlation spectroscopy to monitor the con...

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Detalles Bibliográficos
Autores principales: Borodavka, Alexander, Tuma, Roman, Stockley, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710354/
https://www.ncbi.nlm.nih.gov/pubmed/23422316
http://dx.doi.org/10.4161/rna.23838