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A two-stage mechanism of viral RNA compaction revealed by single molecule fluorescence
Long RNAs often exist as multiple conformers in equilibrium. For the genomes of single-stranded RNA viruses, one of these conformers must include a compacted state allowing the RNA to be confined within the virion. We have used single molecule fluorescence correlation spectroscopy to monitor the con...
Autores principales: | Borodavka, Alexander, Tuma, Roman, Stockley, Peter G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710354/ https://www.ncbi.nlm.nih.gov/pubmed/23422316 http://dx.doi.org/10.4161/rna.23838 |
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