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Small RNAs derived from the 5′ end of tRNA can inhibit protein translation in human cells

Recently, it has been shown that tRNA molecules can be processed into small RNAs that are derived from both the 5′ and 3′ termini. To date, the function of these tRNA fragments (tRFs) derived from the 5′ end of tRNA has not been investigated in depth. We present evidence that conserved residues in t...

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Detalles Bibliográficos
Autores principales: Sobala, Andrew, Hutvagner, Gyorgy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710361/
https://www.ncbi.nlm.nih.gov/pubmed/23563448
http://dx.doi.org/10.4161/rna.24285