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Distinct binding properties of TIAR RRMs and linker region

The RNA-binding protein TIAR is an mRNA-binding protein that acts as a translational repressor, particularly important under conditions of cellular stress. It binds to target mRNA and DNA via its RNA recognition motif (RRM) domains and is involved in both splicing regulation and translational repres...

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Detalles Bibliográficos
Autores principales: Kim, Henry S., Headey, Stephen J., Yoga, Yano M.K., Scanlon, Martin J., Gorospe, Myriam, Wilce, Matthew C.J., Wilce, Jacqueline A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710364/
https://www.ncbi.nlm.nih.gov/pubmed/23603827
http://dx.doi.org/10.4161/rna.24341