Cargando…

Distinct binding properties of TIAR RRMs and linker region

The RNA-binding protein TIAR is an mRNA-binding protein that acts as a translational repressor, particularly important under conditions of cellular stress. It binds to target mRNA and DNA via its RNA recognition motif (RRM) domains and is involved in both splicing regulation and translational repres...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Henry S., Headey, Stephen J., Yoga, Yano M.K., Scanlon, Martin J., Gorospe, Myriam, Wilce, Matthew C.J., Wilce, Jacqueline A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2013
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710364/ https://www.ncbi.nlm.nih.gov/pubmed/23603827 http://dx.doi.org/10.4161/rna.24341

Ejemplares similares

Different modes of interaction by TIAR and HuR with target RNA and DNA
por: Kim, Henry S., et al.
Publicado: (2011)

TIA-1 RRM23 binding and recognition of target oligonucleotides
por: Waris, Saboora, et al.
Publicado: (2017)

Contribution of the first K-homology domain of poly(C)-binding protein 1 to its affinity and specificity for C-rich oligonucleotides
por: Yoga, Yano M. K., et al.
Publicado: (2012)

The SRSF1 linker induces semi-conservative ESE binding by cooperating with the RRMs
por: Cho, Suhyung, et al.
Publicado: (2011)

Novel DNA-binding properties of the RNA-binding protein TIAR
por: Suswam, Esther A., et al.
Publicado: (2005)

Structure and RNA binding of the third KH domain of poly(C)-binding protein 1
por: Sidiqi, M., et al.
Publicado: (2005)

RNA Recognition and Stress Granule Formation by TIA Proteins
por: Waris, Saboora, et al.
Publicado: (2014)

Tandem RNA binding sites induce self-association of the stress granule marker protein TIA-1
por: Loughlin, Fionna E, et al.
Publicado: (2021)

Combined roles of ATP and small hairpin RNA in the activation of RIG-I revealed by solution-based analysis
por: Shah, Neelam, et al.
Publicado: (2018)

Impaired Embryonic Development in Mice Overexpressing the RNA-Binding Protein TIAR
por: Kharraz, Yacine, et al.
Publicado: (2010)

Emerging COVID-19 coronavirus: glycan shield and structure prediction of spike glycoprotein and its interaction with human CD26
por: Vankadari, Naveen, et al.
Publicado: (2020)

Grb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferation
por: Porter, Corrine J, et al.
Publicado: (2007)

A Royal Road to Quantum Theory (or Thereabouts)
por: Wilce, Alexander
Publicado: (2018)

Direct Interaction between Calmodulin and the Grb7 RA-PH Domain
por: Watson, Gabrielle M., et al.
Publicado: (2020)

RNA binding protein TIAR modulates HBV replication by tipping the balance of pgRNA translation
por: Zhang, Ting, et al.
Publicado: (2023)

Enhancing the Bioactivity of Bicyclic Peptides Targeted to Grb7-SH2 by Restoring Cell Permeability
por: Sturre, Natasha P., et al.
Publicado: (2022)

An Appraisal of the Tissue Injury and Repair (TIAR) Theory on the Pathogenesis of Endometriosis and Adenomyosis
por: Habiba, Marwan, et al.
Publicado: (2023)

PTB and TIAR binding to insulin mRNA 3′- and 5′UTRs; implications for insulin biosynthesis and messenger stability
por: Fred, Rikard G., et al.
Publicado: (2016)

Conserved features in TamA enable interaction with TamB to drive the activity of the translocation and assembly module
por: Selkrig, Joel, et al.
Publicado: (2015)

PHAROH lncRNA regulates Myc translation in hepatocellular carcinoma via sequestering TIAR
por: Yu, Allen T, et al.
Publicado: (2021)

Oral available agents in the treatment of RRMS
por: Aupérin, Thierry
Publicado: (2013)

RNA-Binding Proteins Tia-1 and Tiar Link the Phosphorylation of Eif-2α to the Assembly of Mammalian Stress Granules
por: Kedersha, Nancy L., et al.
Publicado: (1999)

Targeted Knockdown of RNA-Binding Protein TIAR for Promoting Self-Renewal and Attenuating Differentiation of Mouse Embryonic Stem Cells
por: Geng, Zhe, et al.
Publicado: (2015)

Genome-wide analysis of TIAR RNA ligands in mouse macrophages before and after LPS stimulation
por: Kharraz, Yacine, et al.
Publicado: (2016)

Conformational rearrangements of RIG-I receptor on formation of a multiprotein:dsRNA assembly
por: Beckham, Simone A., et al.
Publicado: (2013)

Current research in operational quantum logic: algebras, categories, languages
por: Coecke, Bob, et al.
Publicado: (2000)

Pharmacokinetics and pharmacodynamics of natalizumab in pediatric patients with RRMS
por: Ghezzi, Angelo, et al.
Publicado: (2019)

Evidence for cooperative tandem binding of hnRNP C RRMs in mRNA processing
por: Cieniková, Zuzana, et al.
Publicado: (2015)

Insight into the Selectivity of the G7-18NATE Inhibitor Peptide for the Grb7-SH2 Domain Target
por: Watson, Gabrielle M., et al.
Publicado: (2017)

Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7
por: Gunzburg, Menachem J., et al.
Publicado: (2016)

The Stress Granule RNA-Binding Protein TIAR-1 Protects Female Germ Cells from Heat Shock in Caenorhabditis elegans
por: Huelgas-Morales, Gabriela, et al.
Publicado: (2016)

Th17 cells increase in RRMS as well as in SPMS, whereas various other phenotypes of Th17 increase in RRMS only
por: Kalra, S, et al.
Publicado: (2020)

Effect of dimethyl fumarate on lymphocytes in RRMS: Implications for clinical practice
por: Mehta, Devangi, et al.
Publicado: (2019)

Structure of the PCBP2/stem–loop IV complex underlying translation initiation mediated by the poliovirus type I IRES
por: Beckham, Simone A, et al.
Publicado: (2020)

Genistein Targets STING-Driven Antiviral Responses
por: Ullah, Tomalika R., et al.
Publicado: (2022)

Cerebellar Information Processing in Relapsing-Remitting Multiple Sclerosis (RRMS)
por: Lesage, E., et al.
Publicado: (2010)

TIAR and FMRP shape pro-survival nascent proteome of leukemia cells in the bone marrow microenvironment
por: Wolczyk, Magdalena, et al.
Publicado: (2023)

Autoantibodies to the TNF-α translational regulators TIA-1 and TIAR occur frequently in sera of patients with SLE and scleroderma
por: Jimenez-Boj, E, et al.
Publicado: (2002)

TIAR marks nuclear G2/M transition granules and restricts CDK1 activity under replication stress
por: Lafarga, Vanesa, et al.
Publicado: (2018)

Learning ability correlates with brain atrophy and disability progression in RRMS
por: Sormani, Maria Pia, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_j20s5175tf91jcjg14v0hq5hhr