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Archaeal and eukaryotic homologs of Hfq: A structural and evolutionary perspective on Sm function

Hfq and other Sm proteins are central in RNA metabolism, forming an evolutionarily conserved family that plays key roles in RNA processing in organisms ranging from archaea to bacteria to human. Sm-based cellular pathways vary in scope from eukaryotic mRNA splicing to bacterial quorum sensing, with...

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Detalles Bibliográficos
Autores principales: Mura, Cameron, Randolph, Peter S., Patterson, Jennifer, Cozen, Aaron E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710371/
https://www.ncbi.nlm.nih.gov/pubmed/23579284
http://dx.doi.org/10.4161/rna.24538