Functional p53 is required for rapid restoration of daunorubicin-induced lesions of the spleen

BACKGROUND: The tumour suppressor and transcription factor p53 is a major determinant of the therapeutic response to anthracyclines. In healthy tissue, p53 is also considered pivotal for side effects of anthracycline treatment such as lesions in haematopoietic tissues like the spleen. We used a Trp5...

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Detalles Bibliográficos
Autores principales: Herfindal, Lars, Myhren, Lene, Gjertsen, Bjørn Tore, Døskeland, Stein Ove, Gausdal, Gro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710475/
https://www.ncbi.nlm.nih.gov/pubmed/23841896
http://dx.doi.org/10.1186/1471-2407-13-341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710475/
https://www.ncbi.nlm.nih.gov/pubmed/23841896
http://dx.doi.org/10.1186/1471-2407-13-341

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