Derivation of the non-inferiority margin for the evaluation of direct oral anticoagulants in the treatment of venous thromboembolism

BACKGROUND: Direct oral anticoagulants that target a single coagulation factor have been developed as an alternative to standard therapies with heparin and/or vitamin K antagonists. The purpose of this study was to derive non-inferiority margins suitable for randomised clinical studies designed to e...

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Detalles Bibliográficos
Autores principales: Prins, Martin H, Lensing, Anthonie WA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Original Clinical Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710481/
https://www.ncbi.nlm.nih.gov/pubmed/23829521
http://dx.doi.org/10.1186/1477-9560-11-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710481/
https://www.ncbi.nlm.nih.gov/pubmed/23829521
http://dx.doi.org/10.1186/1477-9560-11-13

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