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Haplotype diversity generated by ancient recombination-like events in the MHC of Indian rhesus macaques

The Mamu-A, Mamu-B, and Mamu-DRB genes of the rhesus macaque show several levels of complexity such as allelic heterogeneity (polymorphism), copy number variation, differential segregation of genes/alleles present on a haplotype (diversity) and transcription level differences. A combination of techn...

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Detalles Bibliográficos
Autores principales: Doxiadis, Gaby G. M., de Groot, Nanine, Otting, Nel, de Vos-Rouweler, Annemiek J. M., Bolijn, Maria J., Heijmans, Corrine M. C., de Groot, Natasja G., van der Wiel, Marit K. H., Remarque, Edmond J., Vangenot, Christelle, Nunes, José M., Sanchez-Mazas, Alicia, Bontrop, Ronald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710572/
https://www.ncbi.nlm.nih.gov/pubmed/23715823
http://dx.doi.org/10.1007/s00251-013-0707-8