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Activation of TRPV1 Prevents OxLDL-Induced Lipid Accumulation and TNF-α-Induced Inflammation in Macrophages: Role of Liver X Receptor α

The transient receptor potential vanilloid type 1 (TRPV1) is crucial in the pathogenesis of atherosclerosis; yet its role and underlying mechanism in the formation of macrophage foam cells remain unclear. Here, we show increased TRPV1 expression in the area of foamy macrophages in atherosclerotic ao...

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Detalles Bibliográficos
Autores principales: Zhao, Jin-Feng, Ching, Li-Chieh, Kou, Yu Ru, Lin, Shing-Jong, Wei, Jeng, Shyue, Song-Kun, Lee, Tzong-Shyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710635/
https://www.ncbi.nlm.nih.gov/pubmed/23878415
http://dx.doi.org/10.1155/2013/925171