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Peptide-Based Vaccinology: Experimental and Computational Approaches to Target Hypervariable Viruses through the Fine Characterization of Protective Epitopes Recognized by Monoclonal Antibodies and the Identification of T-Cell-Activating Peptides

Defining immunogenic domains of viral proteins capable of eliciting a protective immune response is crucial in the development of novel epitope-based prophylactic strategies. This is particularly important for the selective targeting of conserved regions shared among hypervariable viruses. Studying...

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Detalles Bibliográficos
Autores principales: Castelli, Matteo, Cappelletti, Francesca, Diotti, Roberta Antonia, Sautto, Giuseppe, Criscuolo, Elena, Dal Peraro, Matteo, Clementi, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710646/
https://www.ncbi.nlm.nih.gov/pubmed/23878584
http://dx.doi.org/10.1155/2013/521231