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Intranasal immunization with a flagellin-adjuvanted peptide anticancer vaccine prevents tumor development by enhancing specific cytotoxic T lymphocyte response in a mouse model

PURPOSE: Human papillomavirus (HPV) is a significant cause of cervical cancer-related deaths worldwide. Because HPV is a sexually transmitted mucosal pathogen, enhancement of antigen-specific mucosal immune response likely serves good strategy for vaccination. However, mucosal vaccines generally do...

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Detalles Bibliográficos
Autores principales: Nguyen, Chung Truong, Hong, Seol Hee, Ung, Thuan Trong, Verma, Vivek, Kim, Soo Young, Rhee, Joon Haeng, Lee, Shee Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Vaccine Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710921/
https://www.ncbi.nlm.nih.gov/pubmed/23858404
http://dx.doi.org/10.7774/cevr.2013.2.2.128