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PHF10 Is Required for Cell Proliferation in Normal and SV40-Immortalized Human Fibroblast Cells

Normal human diploid fibroblasts have limited life span in culture and undergo replicative senescence after 50–60 population doublings. On the contrary, cancer cells typically divide indefinitely and are immortal. Expression of SV40 large T and small t antigens in human fibroblasts transiently exten...

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Detalles Bibliográficos
Autores principales: Banga, S. S., Peng, L., Dasgupta, T., Palejwala, V., Ozer, H. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711003/
https://www.ncbi.nlm.nih.gov/pubmed/20068294
http://dx.doi.org/10.1159/000251960