The C-terminus of S. pombe DDK subunit Dfp1 is required for meiosis-specific transcription and cohesin cleavage

The DDK complex is a conserved kinase complex, consisting of a catalytic subunit, Hsk1 (Cdc7), and its regulatory subunit Dfp1 (Dbf4). This kinase is essential for DNA replication. In this work, we show that dfp1-r35, which truncates the Dfp1 C-terminus zinc finger, causes severe meiotic defects, in...

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Detalles Bibliográficos
Autores principales: Le, Anh-Huy, Mastro, Tara L., Forsburg, Susan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711041/
https://www.ncbi.nlm.nih.gov/pubmed/23862021
http://dx.doi.org/10.1242/bio.20135173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711041/
https://www.ncbi.nlm.nih.gov/pubmed/23862021
http://dx.doi.org/10.1242/bio.20135173

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