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Structural Basis for Activity Regulation and Substrate Preference of Clostridial Collagenases G, H, and T
Clostridial collagenases are among the most efficient enzymes to degrade by far the most predominant protein in the biosphere. Here we present crystal structures of the peptidases of three clostridial collagenase isoforms (ColG, ColH, and ColT). The comparison of unliganded and liganded structures r...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711286/ https://www.ncbi.nlm.nih.gov/pubmed/23703618 http://dx.doi.org/10.1074/jbc.M112.448548 |