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Structural Basis for Activity Regulation and Substrate Preference of Clostridial Collagenases G, H, and T

Clostridial collagenases are among the most efficient enzymes to degrade by far the most predominant protein in the biosphere. Here we present crystal structures of the peptidases of three clostridial collagenase isoforms (ColG, ColH, and ColT). The comparison of unliganded and liganded structures r...

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Detalles Bibliográficos
Autores principales: Eckhard, Ulrich, Schönauer, Esther, Brandstetter, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711286/
https://www.ncbi.nlm.nih.gov/pubmed/23703618
http://dx.doi.org/10.1074/jbc.M112.448548

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