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Transforming Growth Factor-β Induces Transcription Factors MafK and Bach1 to Suppress Expression of the Heme Oxygenase-1 Gene

Transforming growth factor-β (TGF-β) has multiple functions in embryogenesis, adult homeostasis, tissue repair, and development of cancer. Here, we report that TGF-β suppresses the transcriptional activation of the heme oxygenase-1 (HO-1) gene, which is implicated in protection against oxidative inj...

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Detalles Bibliográficos
Autores principales: Okita, Yukari, Kamoshida, Atsushi, Suzuki, Hiroyuki, Itoh, Ken, Motohashi, Hozumi, Igarashi, Kazuhiko, Yamamoto, Masayuki, Ogami, Tomohiro, Koinuma, Daizo, Kato, Mitsuyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711329/
https://www.ncbi.nlm.nih.gov/pubmed/23737527
http://dx.doi.org/10.1074/jbc.M113.450478