Cargando…
Transforming Growth Factor-β Induces Transcription Factors MafK and Bach1 to Suppress Expression of the Heme Oxygenase-1 Gene
Transforming growth factor-β (TGF-β) has multiple functions in embryogenesis, adult homeostasis, tissue repair, and development of cancer. Here, we report that TGF-β suppresses the transcriptional activation of the heme oxygenase-1 (HO-1) gene, which is implicated in protection against oxidative inj...
Autores principales: | Okita, Yukari, Kamoshida, Atsushi, Suzuki, Hiroyuki, Itoh, Ken, Motohashi, Hozumi, Igarashi, Kazuhiko, Yamamoto, Masayuki, Ogami, Tomohiro, Koinuma, Daizo, Kato, Mitsuyasu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711329/ https://www.ncbi.nlm.nih.gov/pubmed/23737527 http://dx.doi.org/10.1074/jbc.M113.450478 |
Ejemplares similares
-
Heme acts through the Bach1b/Nrf2a-MafK pathway to regulate exocrine peptidase precursor genes in porphyric zebrafish
por: Zhang, Shuqing, et al.
Publicado: (2014) -
Bach1 Deficiency and Accompanying Overexpression of Heme Oxygenase-1 Do Not Influence Aging or Tumorigenesis in Mice
por: Ota, Kazushige, et al.
Publicado: (2014) -
Bach1 deficiency reduces severity of osteoarthritis through upregulation of heme oxygenase-1
por: Takada, Tsuyoshi, et al.
Publicado: (2015) -
MafK accelerates Salmonella mucosal infection through caspase-3 activation
por: Xu, Shiyao, et al.
Publicado: (2022) -
Akt regulates the expression of MafK, synaptotagmin I, and syntenin-1, which play roles in neuronal function
por: Ro, Young-Tae, et al.
Publicado: (2010)