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Cell type specificity and structural determinants of IRES activity from the 5′ leaders of different HIV-1 transcripts

Internal ribosome entry site (IRES) RNAs are important regulators of gene expression, but their diverse molecular mechanisms remain partially understood. The HIV-1 gag transcript leader contains an IRES that may be a good model for understanding the function of many other IRESs. We investigated the...

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Detalles Bibliográficos
Autores principales: Plank, Terra-Dawn M., Whitehurst, James T., Kieft, Jeffrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711417/
https://www.ncbi.nlm.nih.gov/pubmed/23661682
http://dx.doi.org/10.1093/nar/gkt358