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PyroHMMsnp: an SNP caller for Ion Torrent and 454 sequencing data

Both 454 and Ion Torrent sequencers are capable of producing large amounts of long high-quality sequencing reads. However, as both methods sequence homopolymers in one cycle, they both suffer from homopolymer uncertainty and incorporation asynchronization. In mapping, such sequencing errors could sh...

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Detalles Bibliográficos
Autores principales: Zeng, Feng, Jiang, Rui, Chen, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711422/
https://www.ncbi.nlm.nih.gov/pubmed/23700313
http://dx.doi.org/10.1093/nar/gkt372