IGF2BP1 promotes mesenchymal cell properties and migration of tumor-derived cells by enhancing the expression of LEF1 and SNAI2 (SLUG)

The oncofetal IGF2 mRNA-binding protein 1 (IGF2BP1) controls the migration and invasiveness of primary as well as tumor-derived cells in vitro. Whether the protein also modulates epithelial-mesenchymal-transition (EMT), a hallmark of tumor progression involved in tumor cell dissemination, remained e...

Descripción completa

Detalles Bibliográficos
Autores principales: Zirkel, Anne, Lederer, Marcell, Stöhr, Nadine, Pazaitis, Nikolaos, Hüttelmaier, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711427/
https://www.ncbi.nlm.nih.gov/pubmed/23677615
http://dx.doi.org/10.1093/nar/gkt410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711427/
https://www.ncbi.nlm.nih.gov/pubmed/23677615
http://dx.doi.org/10.1093/nar/gkt410

Ejemplares similares