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The Fanconi anemia associated protein FAAP24 uses two substrate specific binding surfaces for DNA recognition

To maintain the integrity of the genome, multiple DNA repair systems exist to repair damaged DNA. Recognition of altered DNA, including bulky adducts, pyrimidine dimers and interstrand crosslinks (ICL), partially depends on proteins containing helix-hairpin-helix (HhH) domains. To understand how ICL...

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Detalles Bibliográficos
Autores principales: Wienk, Hans, Slootweg, Jack C., Speerstra, Sietske, Kaptein, Robert, Boelens, Rolf, Folkers, Gert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711432/
https://www.ncbi.nlm.nih.gov/pubmed/23661679
http://dx.doi.org/10.1093/nar/gkt354