Differential roles of human Dicer-binding proteins TRBP and PACT in small RNA processing

During RNA interference and related gene regulatory pathways, the endonuclease Dicer cleaves precursor RNA molecules to produce microRNAs (miRNAs) and short interfering RNAs (siRNAs). Human cells encode a single Dicer enzyme that can associate with two different double-stranded RNA (dsRNA)-binding p...

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Detalles Bibliográficos
Autores principales: Lee, Ho Young, Zhou, Kaihong, Smith, Alison Marie, Noland, Cameron L., Doudna, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711433/
https://www.ncbi.nlm.nih.gov/pubmed/23661684
http://dx.doi.org/10.1093/nar/gkt361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711433/
https://www.ncbi.nlm.nih.gov/pubmed/23661684
http://dx.doi.org/10.1093/nar/gkt361

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