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Activation of a human chromosomal replication origin by protein tethering

The specification of mammalian chromosomal replication origins is incompletely understood. To analyze the assembly and activation of prereplicative complexes (pre-RCs), we tested the effects of tethered binding of chromatin acetyltransferases and replication proteins on chromosomal c-myc origin dele...

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Detalles Bibliográficos
Autores principales: Chen, Xiaomi, Liu, Guoqi, Leffak, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711443/
https://www.ncbi.nlm.nih.gov/pubmed/23658226
http://dx.doi.org/10.1093/nar/gkt368