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Real-time solution measurement of RAD51- and RecA-mediated strand assimilation without background annealing

RAD51 is the central strand exchange recombinase in somatic homologous recombination, providing genomic stability and promoting resistance to DNA damage. An important tool for mechanistic studies of RAD51 is the D-loop or strand assimilation assay, which measures the ability of RAD51-coated single-s...

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Detalles Bibliográficos
Autores principales: Budke, Brian, Chan, Yuen-Ling, Bishop, Douglas K., Connell, Philip P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711447/
https://www.ncbi.nlm.nih.gov/pubmed/23666628
http://dx.doi.org/10.1093/nar/gkt362