Cargando…

Human mitochondrial disease-like symptoms caused by a reduced tRNA aminoacylation activity in flies

The translation of genes encoded in the mitochondrial genome requires specific machinery that functions in the organelle. Among the many mutations linked to human disease that affect mitochondrial translation, several are localized to nuclear genes coding for mitochondrial aminoacyl-transfer RNA syn...

Descripción completa

Detalles Bibliográficos
Autores principales: Guitart, Tanit, Picchioni, Daria, Piñeyro, David, Ribas de Pouplana, Lluís
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711456/
https://www.ncbi.nlm.nih.gov/pubmed/23677612
http://dx.doi.org/10.1093/nar/gkt402