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Human mitochondrial disease-like symptoms caused by a reduced tRNA aminoacylation activity in flies
The translation of genes encoded in the mitochondrial genome requires specific machinery that functions in the organelle. Among the many mutations linked to human disease that affect mitochondrial translation, several are localized to nuclear genes coding for mitochondrial aminoacyl-transfer RNA syn...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711456/ https://www.ncbi.nlm.nih.gov/pubmed/23677612 http://dx.doi.org/10.1093/nar/gkt402 |